Graphene Matrices as Carriers for Metal Ions against Antibiotic Susceptible and Resistant Bacterial Pathogens

Due to the ever-increasing burden of antimicrobial-resistant (AMR) bacteria, development novel antimicrobial agents and biomaterials act as carriers and/or potentiate activity is essential. This study assessed efficacy following ionic metals, silver, gold, palladium, platinum, zinc, gallium alone in combination with graphene matrices (which were coated via a drop casting coating method). The foam was utilized carrier for metals against both, antibiotic susceptible resistant bacterial strains Acinetobacter baumannii,Staphylococcus aureus, Klebsiella pneumoniae Pseudomonas aeruginosa. Ionic palladium platinum demonstrated greatest strains. Scanning electron microscopy (SEM) visualized cellular ultrastructure damage, when bacteria incubated upon alone. suggests that specific metal ions applied could present potential therapeutic option treat AMR infections. application promote activity, provide sustained release approach reduce possible resistance acquisition. In light this study, combinations potentially be further developed part wound dressing.